{"created":"2023-05-15T14:59:44.467534+00:00","id":404,"links":{},"metadata":{"_buckets":{"deposit":"0eb2f716-0d96-4761-87f8-78fcf7d85686"},"_deposit":{"created_by":9,"id":"404","owners":[9],"pid":{"revision_id":0,"type":"depid","value":"404"},"status":"published"},"_oai":{"id":"oai:kamakura-wu.repo.nii.ac.jp:00000404","sets":["1:40"]},"author_link":["825","829","827","824","820","830","821","822","826","828","831","823"],"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"22","bibliographicPageEnd":"11","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"鎌倉女子大学紀要"},{"bibliographic_title":"The journal of Kamakura Women's University","bibliographic_titleLang":"en"}]}]},"item_3_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"肥満解消に植物性化学物質 (フィトケミカル) が有効であることが示唆されている。 そこでマウス脂肪細胞へソバ含有のルチンを作用させ、 悪玉アディポサイトカインである PAI-1 産生を測定した。 ルチン添加で濃度依存的に PAI-1 mRNA 発現量の増加が認められたが、 分泌量およびその活性の減少には有意差を認めなかった。 一方ルチンによる脂肪分解酵素発現は、 用量依存的に増加した。 この結果はルチンが貯蔵脂肪分解に有効であると考えられ、 4 〜 8 時間のルチン曝露による PAI-1 活性は抑制傾向であったことから、 ルチン摂取量や摂取間隔を検討し、 食生活にソバを積極的に取り入れることは健康増進に意義があると考えられた。"}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Phytochemicals have been suggested to be effective for reducing obesity. Rutin, a phytochemical, was added to murine adipocytes, and the production of plasminogen activator inhibitor-1 (PAI-1, an adipo-cytokine), and lipoprotein lipase were measured. The addition of rutin resulted in both a dose-dependent increase in the expression of PAI-1 mRNA and a dose-dependent increase in the expression of lipoprotein lipase mRNA in the adipocytes; however, no change was observed in the secretion or activity of PAI-1. These results suggest that rutin may be effective for reducing body fat, and thus foods containing rutin should be included in the diet."}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN10434900","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09199780","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高橋, 君子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"飯塚, 美伸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石橋, 克之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宍戸, 昌一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"谷口, 亜希子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"眞鍋, 久"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Kimiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iizuka, Yoshinobu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishibashi, Katsuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shishido, Shoichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taniguchi, Akiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Manabe, Hisashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-08-30"}],"displaytype":"detail","filename":"KJ00009707680.pdf","filesize":[{"value":"2.0 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"KJ00009707680.pdf","url":"https://kamakura-wu.repo.nii.ac.jp/record/404/files/KJ00009707680.pdf"},"version_id":"7b8a59b4-63df-4db5-8362-9b0edad06a87"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"フィトケミカル"},{"subitem_subject":"脂肪細胞"},{"subitem_subject":"生活習慣病"},{"subitem_subject":"プラスミノゲンアクチベータインヒビター-1 (PAI-1)"},{"subitem_subject":"リポプロテインリパーゼ (LPL)"},{"subitem_subject":"phytochemicals"},{"subitem_subject":"adipocytes"},{"subitem_subject":"lifestyle-related disease"},{"subitem_subject":"plasminogen activator inhibitor-1 (PAI-1)"},{"subitem_subject":"lipoprotein lipase (LPL)"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_title":"フィトケミカルの保健機能についての検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"フィトケミカルの保健機能についての検討"},{"subitem_title":"Health Function of Phytochemicals"}]},"item_type_id":"3","owner":"9","path":["40"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-30"},"publish_date":"2017-05-30","publish_status":"0","recid":"404","relation_version_is_last":true,"title":["フィトケミカルの保健機能についての検討"],"weko_creator_id":"9","weko_shared_id":-1},"updated":"2023-05-15T15:15:51.569537+00:00"}